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Research Interest:
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Biochemical Pharmaceutics:
I have established the method to identify the components of fibrinolytic enzymes directly from earthworm extracts. At this moment, 11 components of fibrinolytic enzymes from earthworm species Eisenia fetida have been purified in my lab, and their characteristics are studies and analyzed. The focus of my recent research is the earthworm fibrinolytic enzyme Glycosylation decoration analysis.
Industrial Microbiology:
My studies on the screening of glucoamylase producing strains have yielded heat-resistant glucoamylase strains (95 Cencius degrees). Further study on those heat-resistant glucoamylase strains in my lab is still on the way.
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Recent Research Projects:
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(1)
Glycosylation and its functionality in earthworm fibrinolytic enzyme components (PI), 2005-2007
Funded by: Hebei Province Natural Science Fund
Amount: RMB 50,000 |
(2)
Study on the development of earthworm fibrinolytic enzyme thrombolytic drug (Co-PI), 2004-2006
Funded by: Hebei University
Amount: RMB 20,000 |
(3)
Cloning and expression of the Vitreoscilla Hemoglobin Gene in Xanthomonas oryzae (Co-PI), 2003-2005
Funded by: Baoding City Science and Technology Fund
Amount: RMB 20,000 |
(4)
Screening and culture of Strains of Thermostable Glucoamylase (PI), 1999
Amount: RMB 10,000 |
(5)
Modification of xanthan gum strain (PI), 1997
Funded by: RMB 30,000 |
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Selected Publications:
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(1)
Wu Jin Xia, Xiao Yu Zhao,, Rong Pan , Rong Qiao He 2007 Glycosylated trypsin-like proteases from earthworm Eisenia fetida International Journal of Biological Macromolecules 40 (2007) 399–406.
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(2)
WU JinXia, ZHAO Xiaoyu 2005 Fibrin Zymography for Determination of Fibrinolytic Enzymes from Earthworm(Eisenia foetida). Chinese Pharmaceutical Journal，40(21)：1656－1659
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(3)
WU JinXia, ZHAO Xiaoyu 2005 Study on Substrate Specificity of the Earthworm Fibrinolytic Enzymes from(Eisenia foetida), Chinese Journal of zoology,2005，40(4）: 22－28.
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(4)
WU Jinxia , Zhao Xiaoyu 2004 Casein- Plate Method for Determination of Earthworm Fibrinolytic Enzyme. Ziran Zazhi, 26(3)：184-185
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(5)
WU Jinxia, ZHANG Heying 2004 Identification of Thermostable Glucoamylase Components by Starch- PAGE. Journal of Hebei University (Natural Science Edition),2004，24(4)：415-418
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(6)
WU J inXia, ZHAN G HeYing 2002 Separation and Purification of Penicillin Acylase f rom E. coli 108. Chinese Journal of Pharmaceuticals,2002，33(4)：161-163.
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(7)
WU Jinxia ZHANG Heying 2001 Increasing effect of microwave mutation on properties of xanthan gum.2001，11(5)：10－12.
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(8)
WU JinXia, ZhANG HeYing , WANG JianPing , WU JingCai 2001 Amino Acid Composition of theα Chain of Hemoglobin and Amino Acid Sequence of it′s Particular Peptide Fragment From 615 Mouse. Prog. Biochem. Biophys. 2001 ; 28 (2):259-262.
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Copyright 2006